ECS

What is ECS?

Elevate Conditioned Serum or ECS, is an autologous blood based lab service by mail designed for the busy veterinarian. ECS is a serum that contains concentrated amounts cytokines and growth factors such as IL-1RA, IL-10, IL-4, and TGF-β  that mediate inflammation and promote tissue healing. The service can yield up to 40 doses from a 450mL blood bag. These doses can be stored frozen and provide a treatment strategy rather than a one time treatment. Samples are processed in ISO 5 hoods and tested for sterility prior to release.

Frequently Asked Questions

No Processing Time Required

<$12 per mL Increase Margin & Efficiency

High Yield 20 or 40 Doses (4mL Volume Per Dose)

The Benefits & Clinical Applications

ECS is a biological therapy that utilizes your horse’s own blood for the management of pain and inflammation. The injectable solution contains regenerative and anti-inflammatory proteins that work against destructive cells in targeted areas. A key clinical application for ECS is osteoarthritis. 

 

Request ECS Cooler

The Process - How ECS Works

ECS was designed to be convenient for the busy equine veterinarian. This lab service is an Ardent Equine lab service which allows the veterinarian to simply draw blood and administer ECS while we do all of the processing. First, the veterinarian will receive the ECS cooler and then draw blood from their equine patient using our included blood bag. Next, the veterinarian will ship the sample back to Ardent where we will process the blood in our lab. We will then mail the back the ECS where it is then ready to administer to the patient by the veterinarian.

ECS Easy Steps: 1. Receive our ECS cooler 2. Draw blood with our included blood bag 3. Ship it back to Ardent 4. We process the blood in our lab 5. The sample is sent back to the veterinarian 6. Administer as needed, store remainder in freezer

The Science Behind ECS

Endogenous pro-inflammatory cytokines play a significant role in the progression of osteoarthritis with IL-1 being labeled as the major cytokine in joint disease. Elevate ACS contains elevated levels of interleukin-1 receptor antagonist (IL-1Ra) which work to block the destructive effects of IL-1. The solution is also enriched with anti-inflammatory cytokines and growth factors such as IL-1RA, IL-10, IL-4, and TGF-β, which all work to restore joint homeostasis.

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Why Choose ECS Over Intra-Articular Corticosteroids?

ECS can be a safer alternative to intra-articular corticosteroids as steroids do not address the underlying pathogenesis of joint disease. There is concern that the analgesic properties of corticosteroids may improve clinical signs before pathology has resolved, which can lead to the masking of musculoskeletal injuries. This can be hazardous as the overuse of a painless joint may accelerate the deterioration of articular cartilage and injuries may become exacerbated during exercise.

We designed this procedure to have easy processing for the busy veterinarian – all you have to do is pull blood and ship it to us!

Red Blood Cell Free

Safe & Easy

Autologous

Inhibits Inflammatory Cytokines Instead of Masking Pain

All Ardent Equine products are intended to be provided under the care of a licensed veterinarian and in accordance with local regulations and laws.  Interleukin Receptor Antagonist 1 is an all-natural anti-inflammatory cytokine isolated from the patient’s blood and utilized for its potent anti-inflammatory effects.  All treatments should be of localized application at the site of injury or disease. For adverse event reporting forms please email [email protected] or call us at (859) 885-7111.